- Hepatic and intestinal amoebiasis – giardiasis – trichomoniasis
- Treatment and prophylaxis anaerobic bacterial infections.
- Non- specific vaginits
- To eradicate Helicobacter pylori in peptic ulcer disease (in combination with other antimicrobials).
- Hypersensitivity to the drug.
- Pregnancy and lactation.
Metronidazole's side effects are dose related. The most common are gastrointestinal disturbance, nausea, vomiting, unpleasant metallic taste, diarrhea, glosstis, dry mouth, numbness and tingling in the extremities, and nizziness and skin rash.
Drug and Administration:
Tablet should be taken with or after food.
Suspension should be taken at least 1 hour before food.
Amoebiasis adults: 1.5 – 2 g, children 40 mg / kg of body weight in divided doses 2-3 times daily for 5 – 7 days.
Giardiasis adults: 250 or 500 mg 3 times daily for 5 – 7 days.
Giardiasis children: 15 mg l 1 kg of body weight in divided doses for 5 days. It can be renewed after 10 days.
Trichomoniasas adults: 250 mg 3 times or 500 mg twice daily for 7 days and it can be renewed after 7 days. Sexual partner should be treated concomitantly.
1 – 3 years 50 mg 3 times daily for 7 days.
3 – 7 years 100 mg twice daily for 7 days.
7 – 10 years 100 mg 3 times daily for 7 days.
Or 15 mg / kg daily in divided doses.
Anaerobic bacterial infections two tablets 500 mg followed by 500 mg every 8 hours for 7 days.
A box of 20 tablets.