Description
Indications:
- Nosocomial pneumonia
- Community-acquired pneumonia
- Acute bacterial sinusitis
- Acute bacterial exacerbation of chronic bronchitis
- Complicated and uncomplicated skin and skin structure infections
- Chronic bacterial prostatitis
- Complicated and uncomplicated urinary tract infections
- Acute pyelonephritis
- Inhalational anthrax (post-exposure)
- Plague
Contraindications:
Hypersensitivity to any of the drug components.
Side Effects:
Gastrointestinal primarily nausea, vomiting, dizziness and headache.
Dosage and Administration:
Dosage in adults:
| Type of Infection | Dosed Every 24 hours | Duration | |
|
Nosocomial Pneumonia |
750 mg | 7-14 | |
|
Community Acquired Pneumonia |
500 mg | 7-14 | |
|
Community Acquired Pneumonia |
750 mg | 5 | |
| Acute Bacterial Sinusitis | 750 mg | 5 | |
| 500 mg | 10-14 | ||
| Acute Bacterial Exacerbation of Chronic Bronchitis | 500 mg | 7 | |
|
750 mg | 7-14 | |
| Uncomplicated SSSI | 500 mg | 7-10 | |
| Chronic Bacterial Prostatitis | 500 mg | 28 | |
| Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) | 750 mg | 5 | |
|
Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) |
250 mg | 10 | |
| Uncomplicated Urinary Tract Infection | 250 mg | 3 | |
| Inhalational Anthrax (Post-Exposure) in adult | 500 mg | 60 | |
| Plague in adult | 500 mg | 10-14 |
Dosage in pediatrics:
| Type of infection | Dose | Freq. every | Duration |
| Inhalational Anthrax Pediatric patients > 50 kg | 500 mg | 24 hr | 60 days |
| Inhalational Anthrax Pediatric patients < 50 kg and ≥ 6 months of age | 8 mg/kg (not to exceed 250 mg per dose) | 12 hr | 60 days |
| Plague
Pediatric patients > 50 kg |
500 mg | 14 hr | 10-14 days |
| Plague
Pediatric patients < 50 kg and ≥ 6 months of age |
8 mg/kg (not to exceed 250 mg per dose) | 12 hr | 10-14 days |
How Supplied:
- LEVOTOP 250, 500: 10 film coated tablets.
- LEVOTOP 750 mg: 5 or 10 film coated tablets
