{"id":1286,"date":"2020-02-09T08:29:24","date_gmt":"2020-02-09T08:29:24","guid":{"rendered":"http:\/\/barakat.ecastalia.com\/?post_type=product&#038;p=1286"},"modified":"2020-02-11T12:14:03","modified_gmt":"2020-02-11T12:14:03","slug":"bioloric","status":"publish","type":"product","link":"https:\/\/barakat-pharma.com\/product\/bioloric\/","title":{"rendered":"Bioloric"},"content":{"rendered":"<p><strong>PROPERTIES:<\/strong><\/p>\n<p>Allopurinol is known as xantine oxidase inhibitor, so it stops uric acid production by preventing the oxidation of hypoxanthine into xanthine.<\/p>\n<p>Also, it is known as uricostatic agent.<\/p>\n<p><strong>INDICATIONS:<\/strong><\/p>\n<p>BIOLORIC is used for treatment of:<\/p>\n<ul>\n<li>hyperuricemia associated with gout, urate nephropathy caused by urea mono sodium, during cancer chemo &amp; radio therapy.<\/li>\n<li>BIOLORIC is also used in the management of renal calculi due to the deposition of calcium oxalate.<\/li>\n<\/ul>\n<p><strong>CONTRAINDICATIONS:<\/strong><\/p>\n<ul>\n<li>It should not be used with patients who have developed hypersensitivity to the drug.<\/li>\n<li>BIOLORIC is used with caution during pregnancy and lactation (under medical supervision).<\/li>\n<li>Acute attack of gout.<\/li>\n<\/ul>\n<p><strong>SIDE EFFECTS:<\/strong><\/p>\n<p>BIOLORIC may cause nausea, vomiting, diarrhea, skin rash, headache, and may cause leucopenia.<\/p>\n<p><strong>PRECAUTIONS:<\/strong><\/p>\n<ul>\n<li>Treatment should be stopped if any skin reactions or other signs of hypersensitivity develop.<\/li>\n<li>BIOLORIC should be used with caution in patients suffering from renal or hepatic impairment.<\/li>\n<li>BIOLORIC should be used with caution in patients suffering from hypertension and diabetes mellitus.<\/li>\n<\/ul>\n<p><strong>DRUG INTERACTIONS:<\/strong><\/p>\n<ul>\n<li>BIOLORIC should be used with care when administered with Ampicillines or Thiazide diuretics. It may develop an increase of hypersensitivity reactions.<\/li>\n<li>BIOLORIC enhances the activity of captopril, coumarin derivatives, and theophylline.<\/li>\n<\/ul>\n<p><strong>DOSAGE &amp; ADMINISTRATION:<\/strong><\/p>\n<p>Adults:<\/p>\n<p>The starting dose of allopurinol is 100 mg daily gradually increased by 100 mg at weekly intervals.<\/p>\n<p>In case of mild to moderate gout: 100 \u2013 300 mg daily.<\/p>\n<p>In case of moderately severe tophaceous gout: 600 mg daily.<\/p>\n<p>The maximum daily dose should not exceed 900 mg; the single dose should not exceed 300 mg.<\/p>\n<p>When used for the prevention of uric acid nephropathy associated with cancer therapy:<\/p>\n<p>600-900 mg daily generally for 2 or 3 days and starting before the cancer treatment.<\/p>\n<p>The main use of allopurinol in children is for hyperuricaemia associated with cancer or cancer chemotherapy or with enzyme disorders:<\/p>\n<p>For children under 6 years of age: 150 mg.<\/p>\n<p>For children 6 &#8211; 10 years of age: 300 mg, adjusted if necessary after 48 hours.<\/p>\n<p><strong>Note:<\/strong> BIOLORIC is best taken after food, and patients should maintain an adequate fluids intake (about 2 litres daily) to prevent renal calculi formation.<\/p>\n<p><strong>HOW SUPPLIED:<\/strong><\/p>\n<p>Boxes of 30 tablets.<\/p>\n","protected":false},"excerpt":{"rendered":"<p><strong>Dosage Form:<\/strong><br \/>\nTablet<\/p>\n<p><strong>COMPOSITION:<\/strong><br \/>\nEach tablet contains: Allopurinol 100 mg, 300 mg<\/p>\n","protected":false},"featured_media":1289,"template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":""},"product_cat":[58],"product_tag":[],"_links":{"self":[{"href":"https:\/\/barakat-pharma.com\/wp-json\/wp\/v2\/product\/1286"}],"collection":[{"href":"https:\/\/barakat-pharma.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/barakat-pharma.com\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/barakat-pharma.com\/wp-json\/wp\/v2\/media\/1289"}],"wp:attachment":[{"href":"https:\/\/barakat-pharma.com\/wp-json\/wp\/v2\/media?parent=1286"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/barakat-pharma.com\/wp-json\/wp\/v2\/product_cat?post=1286"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/barakat-pharma.com\/wp-json\/wp\/v2\/product_tag?post=1286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}