Description
Hyoscine works at specific areas on a cell called receptors. The receptors that hyoscine interacts with are called muscarinic receptors (there are many different types of receptor). Hyoscine works by preventing certain chemicals produced by the body, from interacting with the muscarinic receptors located on the smooth muscle of the gut. This causes the gut muscle to relax, removing the pain of colic resulting from the gut muscle contraction and spasm. This drug can also be used to treat painful periods in women.
BARCOLAN COMPOUND is a combination between Hyoscine-N-Butylbromide and Paracetamol which is known for its analgesic and antipyretic properties.
INDICATIONS:
- Abdominal pain associated with menstrual periods.
- Abdominal pain which comes and goes (colic).
- Irritable Bowel Syndrome.
PRECAUTIONS:
Children, Diarrhea, Down’s syndrome, Fever (pyrexia), Heart attack, Heartburn, High blood pressure, Hyperthyroidism, Inflammation of the bowel and back passage, People over the age of 75 years.
CONTRAINDICATIONS:
- Abnormal muscle weakness.
- Enlarged prostate.
- Failure of function of part of the gut causing an obstruction (paralytic ileus).
- Glaucoma.
- Life long inherited blood diseases which can cause a variety of symptoms, including mental health problems (porphyrias).
- Narrowing of the outlet of the stomach making it difficult for food to pass into the intestines (pyloric stenosis).
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
PREGNANCY AND BREASTFEEDING:
- This medicine should be used with caution during pregnancy, and only if the expected benefit to the mother is greater than the possible risk to the fetus. Seek medical advice from your doctor.
- This medicine should be used with caution by breastfeeding mothers, and only if the expected benefit to the mother is greater than the possible risk to the baby. Seek medical advice from your doctor.
SIDE EFFECTS:
- Faster than normal heart beat (tachycardia)
- Increased need to pass urine
- Blurred vision
- Dry mouth
- Constipation
- Difficulty in passing urine (urinary retention)
DRUG INTERACTIONS:
The effects of this drug are increased if the patient is also taking: alcohol, nefopam and disopyramide. Hyoscine-N-butylbromide decreases the effects of the following drugs: ketoconazole, certain anti-psychotics, cisapride, levodopa, metoclopramide, domperidone, sublingual nitrates and parasympathomimetics. The following drugs increase the side-effects of Hyoscine-N-butylbromide: other hyoscine-N-butylbromide like drugs, certain anti-depressants, antihistamines, certain anti-psychotics and amantadine.
DOSAGE:
Tablets:
Adults: 2 BARCOLAN or BARCOLAN COMPOUND tablets (20 mg) 4 times daily.
Children (6 -12 years): 1 BARCOLAN or BARCOLAN COMPOUND tablet (10 mg) 3 times daily.
Irritable bowel syndrome: 1 BARCOLAN or BARCOLAN COMPOUND tablet (10 mg) 3 times daily increased if required up to 2 BARCOLAN or BARCOLAN COMPOUND tablets (20 mg)
4 times daily.
Suppositories:
Adults and children over 14 years:
1 BARCOLAN or BARCOLAN COMPOUND suppository 1-3 times daily.
Syrup:
Children (1-6 years): 1 spoonful (5 ml) 3-5 times daily.
Children over 6 years: 1-2 spoonfuls (5 ml) 3-5 times daily.
HOW SUPPLIED:
- BARCOLAN film coated Tablets: Box of 20, 30, and 500 tablets.
- BARCOLAN Suppositories: Box of 10 suppositories.
- BARCOLAN Syrup: Bottle of 100 ml Syrup.
- BARCOLAN COMPOUND film coated Tablets: Box of 20, 500 tablets.
- BARCOLAN COMPOUND Suppositories: Box of 10 suppositories.
STORAGE CONDITIONS:
Keep out of the reach of children in a dry place at temperature below 25°C.
