Description
Indications:
Pain and inflammatory of: rheumatoid arthritis, osteoarthritis, primary dysmenorrhea, pyrexia, postoperative analgesia, migraine, dental pain.
Contraindications:
- Hypersensitivity to any of the drug components.
- Hypersensitivity to aspirin or other non-steroidal anti-inflammatory drugs (e.g. asthma, rhinitis or urticaria).
- Active gastro-intestinal bleeding or ulceration.
- History of gastro-intestinal bleeding or perforation related to previous NSAID therapy.
- History of recurrent gastro-intestinal hemorrhage or ulceration (two or more distinct episodes).
- History of ulcerative colitis, Crohn’s disease.
- Severe heart failure.
- Severe liver failure.
- Severe renal failure (glomerular filtration below 30 ml/min).
- Increased tendency or active bleeding.
- Third trimester of pregnancy.
Side effects:
Nausea, vomiting, gastrointestinal hemorrhage
Dosage and Administration:
It should be swallowed with water with or after food
ADULTS:
Initial dose of ibuprofen is 1200 mg-1800 mg daily in divided doses, some patients could be maintained on dose of 600 – 1200 mg daily.
Maximum dose is 2400 mg daily in divided doses.
PRIMARY DYSMENORRHEA:
The initial dose is 400- 800 mg, then 400 mg 4 – 6 hourly with a maximum total daily dose of 1600 mg.
CHILDREN:
The daily dose is 20 mg/kg in divided doses.
In juvenile rheumatoid arthritis up to 40 mg/kg in divided doses.
In children weighing less than 30 kg the total dose given in 24 hours should not exceed 500 mg.
How Supplied:
- IPOFENE Oral Suspension: Bottles of 100 ml, 150 ml.
- IPOFENE 400 mg: Boxes of 20, 30, 500 film coated tablets.
- IPOFENE 600 mg: Boxes of 20 film coated tablets.
- IPOFENE Retard 800 mg: Boxes of 20 film coated tablets.
