Loperamide is an anti-diarrheal agent, it is a synthetic opioid analogue which inhibits gut motility and may also reduce gastrointestinal secretions
Pyramide is used as an adjunct in the management of acute and chronic diarrheas.
- Hypersensitivity to drug.
- Patients with dysentery or if constipation must be avoided.
- Infants and children under 4 years.
- May cause: abdominal pain, nausea, dry mouth, dizziness, skin rashes, paralytic ileus particularly in infants and young children.
- A toxic hypertrophy in large intestine.
- May causes breakdown in the central nervous system in overdoses.
- The drug should not taken for more than two days – except if the physician decides that.
- The drug should not be used in overdoses without the supervision of the physician who’ll give the correct decision.
- PYRAMIDE should be used with caution in young children.
- If the diarrhea still continues after continuous three days of treatment. A medical supervision and a medical decision is essential.
- Pyramide should be used with caution in patients with hepatic dysfunction, inflammatory bowel disease or pseudomembranous colitis.
- It should be used during pregnancy only if dearly needed.
- Pyramide should be used with caution during lactation
Dosage and administration:
Adults: the initial dose is 4 mg followed by 2 mg after each loose stool to a maximum 16 mg daily. The usual daily dose is 6 to 8 mg.
Children 4-8 years: 1 mg four times daily up to 3 days. Children 9-12 years: 2 mg tour times daily up to 5 days.
Adults: the usual initial dose is 4-8 mg daily in divided doses.
If no improvement has been observed after treatment with 16 mg daily for at least 10 days, further administration is unlikely to be of benefit
Boxes of 20 Capsules.